KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SAMHD1
All Species:
18.18
Human Site:
Y507
Identified Species:
33.33
UniProt:
Q9Y3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Z3
NP_056289.2
626
72201
Y507
V
D
V
I
N
M
D
Y
G
M
Q
E
K
N
P
Chimpanzee
Pan troglodytes
XP_514624
382
43769
C266
L
I
P
E
E
D
I
C
F
I
K
E
Q
I
V
Rhesus Macaque
Macaca mulatta
XP_001097562
728
83194
Y609
V
D
V
I
N
M
D
Y
G
M
Q
E
N
N
P
Dog
Lupus familis
XP_542986
665
76981
Y546
V
D
V
I
N
M
D
Y
G
M
E
D
K
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60710
627
72632
F509
V
E
L
K
A
E
D
F
I
V
D
V
I
N
V
Rat
Rattus norvegicus
XP_230789
677
77635
F559
V
E
L
K
A
E
D
F
I
V
D
V
I
N
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJL9
614
70202
F490
V
E
L
T
A
E
D
F
I
V
D
V
V
N
M
Frog
Xenopus laevis
Q6INN8
632
72730
Y513
V
D
V
I
H
M
D
Y
G
M
K
E
Q
N
P
Zebra Danio
Brachydanio rerio
Q502K2
622
71649
Y486
V
S
V
I
H
M
D
Y
G
M
K
E
K
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09374
587
66474
M469
K
D
I
Q
F
T
V
M
H
S
V
L
G
R
G
Sea Urchin
Strong. purpuratus
XP_784786
594
68895
V478
L
D
P
D
D
L
V
V
H
E
V
K
M
D
Y
Poplar Tree
Populus trichocarpa
XP_002312899
477
54770
T361
I
E
N
F
K
D
V
T
A
Q
D
I
V
C
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568580
473
54655
V357
K
I
D
H
F
K
A
V
T
P
Q
D
I
I
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.9
79.5
73.5
N.A.
73.3
65.8
N.A.
N.A.
60
61.8
60.8
N.A.
N.A.
N.A.
22.5
46.8
Protein Similarity:
100
60.2
82.4
83.6
N.A.
83.2
76.2
N.A.
N.A.
74.9
75.3
74.1
N.A.
N.A.
N.A.
40.8
64.2
P-Site Identity:
100
6.6
93.3
86.6
N.A.
20
20
N.A.
N.A.
20
80
80
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
33.3
93.3
100
N.A.
46.6
46.6
N.A.
N.A.
46.6
100
93.3
N.A.
N.A.
N.A.
13.3
40
Percent
Protein Identity:
28.2
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
45
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
24
0
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
8
% C
% Asp:
0
47
8
8
8
16
62
0
0
0
31
16
0
8
0
% D
% Glu:
0
31
0
8
8
24
0
0
0
8
8
39
0
0
0
% E
% Phe:
0
0
0
8
16
0
0
24
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
39
0
0
0
8
0
8
% G
% His:
0
0
0
8
16
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
8
16
8
39
0
0
8
0
24
8
0
8
24
16
0
% I
% Lys:
16
0
0
16
8
8
0
0
0
0
24
8
24
0
0
% K
% Leu:
16
0
24
0
0
8
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
39
0
8
0
39
0
0
8
0
16
% M
% Asn:
0
0
8
0
24
0
0
0
0
0
0
0
8
62
0
% N
% Pro:
0
0
16
0
0
0
0
0
0
8
0
0
0
0
39
% P
% Gln:
0
0
0
8
0
0
0
0
0
8
24
0
16
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
8
% S
% Thr:
0
0
0
8
0
8
0
8
8
0
0
0
0
0
0
% T
% Val:
62
0
39
0
0
0
24
16
0
24
16
24
16
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _